I have been plagued with cold sores as long as I can remember. As I have aged, they have spread from my lips to everywhere, head to toe. When I had one start I tried it and it cleared up in a day. I had another start in my eyebrow and wasnāt thinking about it as a cold sore. After a couple days of āannoyanceā I thought it might be. I used the cold sore calmer a few times that day and the next day it had stopped being annoying. I absolutely LOVE this salve.